杜英峰，河北邯郸市人，汉族，无党派人士，教授，博士生导师。1998年毕业于5848vip威尼斯电子游戏，获理学学士学位，2004年毕业于5848vip威尼斯电子游戏药物分析专业，获医学硕士学位，2011年毕业于5848vip威尼斯电子游戏药理学专业，获博士学位。河北省三三三人才获得者，河北省药学会中药分析委员会常委，河北省中药学会中药质量专业委员会常委。

目前主要从事药物质量控制和体内过程研究。在药物质量控制方法学，中药多组分表征技术，中药生物体内化学成分及其代谢物检测技术等方面进行了大量研究。另外基于液质联用等现代先进的分析方法，对中药香茶菜属植物中的贝壳杉烷二萜成分及其同分异构体快速识别和分析，总结了此类化合物的质谱裂解规律，建立了质谱库检索和特征离子碎片相结合的中药定性研究方法，为中药的质量控制提供有价值的依据。课题组目前发表科研论文五十余篇，其中以第一或通讯作者在专业领域内知名杂志上发表SCI论文30余篇，中文核心期刊和CSCD期刊收录20余篇。

近年来，主持国家自然基金1项，河北省自然基金3项，河北省食品药品监督管理局课题和河北省中医药管理局课题各1项。作为主研人参与国家自然基金3项，省自然基金课题、省食品药品监督管理局、省中医药管理局、省教育厅和省卫生厅课题多项，多次获得河北省优秀硕士论文指导教师称号。

获河北省科技进步二等奖2项，其中排名第一1项；河北省科技进步三等奖3项，其中排名第二1项，排名第三1项；中华中医药学会科学技术三等奖2项；河北省中医药学会科学技术一等奖2项，其中排名第一1项，排名第二2项；河北省医学会科学技术一等奖1项，排名第3。

科研业绩

1.The therapeutic effect of wine-processed Corni Fructus on chronic renal failure in rats through the interference with the LPS/IL-1-mediated inhibition of RXR function.Journal of Ethnopharmacology 321 (2024) 117511.通讯作者

2.The bioavailability enhancement and insight into the action mechanism of poorly soluble natural compounds from co-crystals preparation: oridonin as an example..Phytomedicine,2024,122,155179. 通讯作者

3.Systematically uncovering the absorbed effective substances of Radix Scutellaria-licorice drug pair in rat plasma against COVID-19 using a combined UHPLC-Q-TOF-MS analysis and target network pharmacology..Plos one,2023,0289121. 通讯作者

4.Integrated metabolomics, network pharmacology and molecular docking to reveal the mechanisms of Isodonexcisoides against drug induced liver injury..Biomedical Chromatography. 2023; e5682. 通讯作者

5.Investigation of pharmacodynamic material basis of AnemarrhenaeRhizoma and its processed products based on plant metabolomics and molecular docking technology..Rapid Commun Mass Spectrom. 2023;37:e9473. 通讯作者

6.Characterization of Fritillariaecirrhosaebulbus from multiple sources by potential Q-marker based on metabolomics and network pharmacology..Rapid Commun Mass Spectrom. 2023;37:e9403. 通讯作者

7.Study on mechanism of hepatoprotective effect of Chrysanthemum morifolium Ramat. based on metabolomics with network analysis and network pharmacology..Journal of Chromatography B,2023, 1222,123711. 通讯作者

8.An integrated strategy to explore the wine-processed mechanism of CorniFructus on chronic renal failure based on metabolomics, network analysis and bioinformatics approachs..Journal of Pharmacy and Pharmacology, 2023, Volume 75, Issue 4,  559–573. 通讯作者

9.A holistic comparison of flavor signature and chemical profile in different harvesting periods of Chrysanthemum morifolium Ramat. based on metabolomics combined with bioinformatics and molecular docking strategy..RSC Adv., 2022, 12, 34971–34989. 通讯作者

10.Screening and capability assessment of tyrosinase inhibitors in Isodonexcisoides by ultrafiltration coupled with UHPLC-Q-TOF-MS and molecular docking technology..Chemistry & Biodiversity,2022, 19, e202200748.通讯作者

11.Novel insight into the mechanism underlying synergistic cytotoxicity from two components in 5-Fluorouracil-phenylalanine co-crystal based on cell metabolomics..European Journal of Pharmaceutics and Biopharmaceutics, 180 (2022) 181–189. 通讯作者

12.An integrated strategy to reveal the potential anti-asthma mechanism of peimine by metabolite profiling, network pharmacology, and molecular docking..Journal of Separation Science. 2022;45:2819–2832. 通讯作者

13.A practical technique for rapid characterisation of ent-kauranediterpenoids in Isodonserra (Maxim.) Hara by UHPLC-Q-TOF-MS/MS..Phytochemical Analysis,2022,4:517-532. 通讯作者

14.An integrative method based on UHPLC-Q-TOF-MS/MS combined with metabolomics to authenticate Isodonrubescens..Analytical Biochemistry, 2021. 629,114297.通讯作者

15.Cell metabolomics to study the cytotoxicity of carbon black nanoparticles on A549 cells using UHPLC-Q/TOF-MS and multivariate data analysis..Science of the Total Environment, 2020, 68: 134122. 通讯作者

16.A novel strategy for the characterization of  glaucocalyxin A metabolites in vivo  and in vitro by UHPLC-Q-TOF-MS based on DDA and DIA data acquisitions.RSC Advances, 2020, 10: 10431-10446. 通讯作者

17.Chemical profiling and total quality assessment of Isodon japonica using data-independent acquisition mode combined with superimposed multiple product ion UHPLC-Q-TOF-MS and chemometric analysis..RSC Adv, 2019, 9, 1403-1418. 通讯作者

18.Metabolites identification of (+)-usnic acid in vivo by ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry..Fitoterapia, 2019,133, 85-95. 通讯作者

19.UHPLC-Q-TOF-MS/MS-oriented characteristic components dataset and multivariate statistical techniques for the holistic quality control of Usnea..RSC Adv, 2018, 8, 15487-15550. 通讯作者

20.A practical strategy for the characterization   of ponicidin metabolites in vivo and in vitro  by UHPLC-Q-TOF-MS based on nontargeted SWATH data acquisition.Journal of Pharmaceutical and Biomedical Analysis,2017,145,865-878.通讯作者

21.Identification and comparative oridonin metabolism in different species liver microsomes by using   UPLC-Triple-TOF-MS/MS and PCA..Analytical Biochemistry,2016,511: 61-73.通讯作者

22.Differentiation of Isodon japonica and Adulterants Based on Identification andQuantitation 14 Diterpenoids Using LC-MS-MSLibrary Search Approach and Hierarchical Cluster Analysis..Journal of Chromatographic Science, 2016, 54 (3):367-376.

23.Simultaneous Quantification of 11 Constituentsin Wuji Pill Using Ultra Performance Liquid Chromatography Coupled With a Triple Quadrupole Electrospray Tandem Mass Spectrometry..Journal of Chromatographic Science, 2016, 54 (2):237-245.

24.Simultaneous determination of ginsenoside Rb1, naringin, ginsenosideRb2and oridonin in rat plasma by LC–MS/MS and its application to apharmacokinetic study after oral administration of Weifuchun tablet..Journal of Chromatography B, 2015,1000:112-119. 通讯作者

25.Identification of metabolites of oridonin in rats with a single run onUPLC-Triple-TOF-MS/MS system based on multiple mass defect filterdata acquisition and multiple data processing techniques..Journal of Chromatography B, 2015,1006:80-92. 通讯作者

26.Quantitative analysis of ten diterpenoids in rat bile after oral administration of Isodon rubescens extract by high performance liquid chromatography-electrospray ionization tandem mass spectrometry..Journal of Liquid Chromatography & Related Technologies, 2013, 36, 1264-1279.第一作者

27.A sensitive analysis method for 7 diterpenoids in rat plasma by liquid chromatography–electrospray ionization mass spectrometry and its application to pharmacokinetic study of Isodon serra extract. .Journal of Chromatography A, 2011, 1218:7771-7780. 

28.A novel analysis method for diterpenoids in rat plasma by liquid chromatography-electrospray ionization mass spectrometry. .Analytical Biochemistry, 2010,407:111-119. 第一作者

29.Simultaneous qualitative and quantitative analysis of 28 components in Isodon rubescens by HPLC-ESI-MS/MS. .Journal of Separation Science, 2010,33:545-557.第一作者

30.Rapid method for simultaneous determination of 20 components in Isodon nervosa by high-performance liquid chromatography-electrospray ionisation tandem mass spectrometry.  Phytochemical Analysis, 2010,21,416-427. 第一作者

34.河北省科技进步二等奖，基于液质联用方法的冬凌草的质量控制和药物代谢轮廓研究 .第一完成人（2015JB2045-1）

35.河北省科技进步三等奖，河北道地药材指纹图谱研究与质量评价.第二完成人（2014JB3154-2）

36.河北省科技进步三等奖，间尼索地平（临床前）质量标准及药代动力学研究.第三完成人（2009JB3132-3）

37.河北省中医药学会科学技术一等奖，基于液质联用方法的冬凌草的质量控制和药物代谢轮廓研究.第一完成人（20141001）